SARS-CoV-2 and influenza virus ion channel structures

Mei Hong

PSFC

Tuesday, January 19, 2021

1:00pm

Virtual

IAP Seminars

Many human viruses have cation-selective transmembrane ion channels that are important for the virus lifecycle and pathogenesis.  Researchers at MIT’s Hong Lab have determined the structures of a SARS-CoV-2 viroporin, the envelope protein E, and the influenza viroporin, M2, using nuclear magnetic resonance spectroscopy. This molecular structural information sets the stage for developing antiviral drugs to inhibit these viroporins.  

For Zoom link contact info@psfc.mit.edu.